339 /10:15 Missense mutations disrupting the ATPase domain of CHD3 cause a novel neurodevelopmental syndrome with intellectual disability, macrocephaly and impaired speech and language. L. Snijders Blok, J. Rousseau, J. Twist, S. Ehresmann, L. Faivre, J. Thevenon, M. Assoum, L. Rodan, C. Nowak, J. Douglas, . Swoboda, . Steeves, I. Sahai, . Stumpel, P. Wheeler, M. Willing, E. Fiala, A. Kochhar, . Gibson, . Cohen, R. Agbahovbe, J. Rankin, . Anderson, S. Skinner, R. Louie, H. Warren, A. Afenjar, R. Lewandowski, J. Propst, M. Choi, . Chae, S. Price, M. Cho, C. Zweier, A. Reis, M. Bialer, C. Moore, M. Swinkels, . Brilstra, . Monroe, G. van Haaften, R. Newbury-Ecob, the DDD study, L.D. Shriberg, P. Deriziotis, T. Kleefstra, . Brunner, M. Takaku, . Roberts, . Petrovich, S. Machida, H. Kurumizaka, . Wade, . Fisher, . Campeau.
Like a great book, The Closing of the American Mind sparks intense disagreements. Is Bloom’s description of the principles of the American Founding accurate? Does he caricature the flat souls of his students? Do philosophical ideas really have the power he attributes to them? Is his genealogy of ideas accurate? How does he understand the relationship between philosophy and morality? What does nature teach about the moral life? Can the restoration of a Great Books education in the university really be the remedy for the crisis of the West?