Tcp phd thesis

WUSA produces the campus magazine Tertangala . Tertangala has a 45-year history, making it older than the University of Wollongong itself. It began in 1962, when the university was an external campus of the University of New South Wales. The magazine features student investigative and feature articles, news, artwork, opinion, film and music reviews, as well as interviews and editorials. Submissions from staff and students (including student association representatives) makes up the bulk of the magazines content, however submissions from other members of the community are also accepted. Tertangala is produced eight times a year.

Metastatic disease is a principal cause of death from breast cancer. There is a need to develop new anti-cancer agents specifically designed to target physiological aspects unique to cancer cells that spare normal tissue and can be tailored to individual patients. To this end, the Khaled lab discovered CT20p. The cancer-specific action of CT20p is based on its interaction and inhibition of a protein folding complex called chaperonin containing TCP-1 or CCT. Inhibiting CCT with CT20p compromises the cytoskeleton in breast cancer cells, which resulted in loss of cell adherence and migration, leading to cell death. The objective of our research is to investigate the levels of CCT and its client proteins in breast tumors and correlate results with susceptibility to CT20p to develop a personalized treatment approach for breast cancer. We hypothesize that CCT is a driver of carcinogenesis in the subgroup of breast cancer patients that develop late stage and disseminated disease and serves as a viable target for therapeutic intervention. Our work could yield a new personalized therapeutic strategy for breast cancer, for example, combining CT20p with immunotherapy like checkpoint blockage drugs, to eliminate drug-resistant cancer cells and prevent disease recurrence and metastasis.

Very interesting. I’m in Canada (just got here recently) and have noticed the same behavior. Back in the ., I could keep an idle connection open indefinitely (weeks, months, etc.), whereas here I return to my terminal and see closed connections if I leave my machine for a bit (haven’t tested to see exactly how long, but it seems quite short, definitely under an hour). I blame my either my ISP (TekSavvy) or its cable provider (Rogers). It’s downright wrong to close people’s TCP connections just because you feel like it. What if I were streaming something from a server and the server had a hiccup and stopped streaming for some time: are they going to close that connection, too, and force me to restart the entire stream just because they feel like it? Canada is weird in this respect. Whether it’s due to bureaucracy or incompetence, it doesn’t matter, it just plain sucks and makes no sense at all.

Tcp phd thesis

tcp phd thesis


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